A-3 Hydrochloride
| CAS No. | 78957-85-4 | Cat. No. | BCP37347 |
| Name | A-3 Hydrochloride | ||
| Synonyms | A3 hydrochloride;A3 HCl; | ||
| Formula | C12H14Cl2N2O2S | M. Wt | 321.22 |
| Description | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively. | ||
| Pathways | Neuro Signaling Pathway Cell Cycle/DNA Damage GPCR/G Protein Wnt/Stem Cell Epigenetics | ||
| Targets | Casein Kinase CaMK PKA PKC | ||
Structure
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