A-3 Hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 78957-85-4 | Cat. No. | BCP37347 |
| Name | A-3 Hydrochloride | ||
| Synonyms | A3 hydrochloride;A3 HCl; | ||
| SMILES | C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCN.Cl | ||
| Chemical Name | |||
| Formula | C12H14Cl2N2O2S | M. Wt | 321.22 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively. | ||
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