SRT2183

  • Chemical Properties
CAS No. 1001908-89-9 Cat. No. BCP37408
Name SRT2183
Synonyms SRT 2183; SRT-2183;
Formula C27H24N4O2S M. Wt 468.57
  • Biological Activity
Description SRT2183 is a Sirt1 activator, currently being developed by Sirtris Pharmaceuticals. SRT2183 has similar activity in the body to another SIRT1 activator SRT1720 , but is closer in potency to resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. However, the claim that SRT2183 is a SIRT1 activator has been questioned and further defended.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets Sirtuin 

Structure

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