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CAS No. | 1001908-89-9 | Cat. No. | BCP37408 |
Name | SRT2183 | ||
Synonyms | SRT 2183; SRT-2183; | ||
SMILES | C1CN(CC1O)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=CC6=CC=CC=C6C=C5 | ||
Chemical Name | |||
Formula | C27H24N4O2S | M. Wt | 468.57 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SRT2183 is a Sirt1 activator, currently being developed by Sirtris Pharmaceuticals. SRT2183 has similar activity in the body to another SIRT1 activator SRT1720 , but is closer in potency to resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. However, the claim that SRT2183 is a SIRT1 activator has been questioned and further defended. |
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