Orelabrutinib
| CAS No. | 1655504-04-3 | Cat. No. | BCP37603 |
| Name | Orelabrutinib | ||
| Synonyms | ICP-022; ICP022; ICP 022; | ||
| Formula | C26H25N3O3 | M. Wt | 427.50 |
| Description | Orelabrutinib is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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