Orelabrutinib New
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CAS No. | 1655504-04-3 | Cat. No. | BCP37603 |
Name | Orelabrutinib | ||
Synonyms | ICP-022; ICP022; ICP 022; | ||
SMILES | C=CC(=O)N1CCC(CC1)C2=NC(=C(C=C2)C(=O)N)C3=CC=C(C=C3)OC4=CC=CC=C4 | ||
Chemical Name | |||
Formula | C26H25N3O3 | M. Wt | 427.50 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Orelabrutinib is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK. |
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