ML418

  • Chemical Properties
CAS No. 1928763-08-9 Cat. No. BCP37608
Name ML418
Synonyms ML-418; ML 418;
Formula C19H24ClN3O3 M. Wt 377.87
  • Biological Activity
Description ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy.
Pathways Ion Channel/Membrane Transporter 
Targets Potassium Channel 

Structure

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