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CAS No. | 1928763-08-9 | Cat. No. | BCP37608 |
Name | ML418 | ||
Synonyms | ML-418; ML 418; | ||
SMILES | CC(C)OC(=O)NC1CCN(CC1)CC2=CC(=C3C=CC=NC3=C2O)Cl | ||
Chemical Name | |||
Formula | C19H24ClN3O3 | M. Wt | 377.87 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. |
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