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ML418 Chemical Structure

ML418

Data Sheet For research use only. Not for human use.
Cat. No. :BCP37608CAS No. :1928763-08-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1928763-08-9 Cat. No. BCP37608
Name ML418
Synonyms ML-418; ML 418;
SMILES CC(C)OC(=O)NC1CCN(CC1)CC2=CC(=C3C=CC=NC3=C2O)Cl
Chemical Name
Formula C19H24ClN3O3 M. Wt 377.87
Purity 98% Storage Store at 4-8°C
Description ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy.
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