AC1903

  • Chemical Properties
CAS No. 831234-13-0 Cat. No. BCP37804
Name AC1903
Synonyms AC 1903; AC-1903;
Formula C19H17N3O M. Wt 303.36
  • Biological Activity
Description AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model.
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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