AC1903 New
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CAS No. | 831234-13-0 | Cat. No. | BCP37804 |
Name | AC1903 | ||
Synonyms | AC 1903; AC-1903; | ||
SMILES | C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4 | ||
Chemical Name | |||
Formula | C19H17N3O | M. Wt | 303.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model. |
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