5F 203
| CAS No. | 260443-89-8 | Cat. No. | BCP37820 |
| Name | 5F 203 | ||
| Synonyms | 5-fluoro 203;5F 203;NSC703786;NSC 703786;NSC-703786; | ||
| Formula | C14H11FN2S | M. Wt | 258.32 |
| Description | 5F 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest. In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK. | ||
| Pathways | Others Pathway | ||
| Targets | AhR | ||
Structure
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