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CAS No. | 260443-89-8 | Cat. No. | BCP37820 |
Name | 5F 203 | ||
Synonyms | 5-fluoro 203;5F 203;NSC703786;NSC 703786;NSC-703786; | ||
SMILES | CC1=C(C=CC(=C1)C2=NC3=C(S2)C=CC(=C3)F)N | ||
Chemical Name | |||
Formula | C14H11FN2S | M. Wt | 258.32 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 5F 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest. In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK. |
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