GSK-843

  • Chemical Properties
CAS No. 1601496-05-2 Cat. No. BCP37845
Name GSK-843
Synonyms GSK843;GSK 843;
Formula C19H15N5S2 M. Wt 377.49
  • Biological Activity
Description GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM.
Pathways Apoptosis Pathway 
Targets RIP 

Structure

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