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CAS No. | 1601496-05-2 | Cat. No. | BCP37845 |
Name | GSK-843 | ||
Synonyms | GSK843;GSK 843; | ||
SMILES | CC1=NN(C(=C1)C2=CN=C(C3=C2SC=C3C4=CC5=C(C=C4)SC=N5)N)C | ||
Chemical Name | |||
Formula | C19H15N5S2 | M. Wt | 377.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. |
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