TX1-85-1
| CAS No. | 1603845-32-4 | Cat. No. | BCP37896 |
| Name | TX1-85-1 | ||
| Synonyms | |||
| Formula | C32H36N8O3 | M. Wt | 580.68 |
| Description | TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It is the first selective HER3 ligand that interacts with cys721 in the ATP-binding pocket of HER3. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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