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CAS No. | 1603845-32-4 | Cat. No. | BCP37896 |
Name | TX1-85-1 | ||
Synonyms | |||
SMILES | CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=NC=NC(=C4C(=N3)C5=CC(=C(C=C5)OC6=CC=CC=C6)NC(=O)C=C)N | ||
Chemical Name | |||
Formula | C32H36N8O3 | M. Wt | 580.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It is the first selective HER3 ligand that interacts with cys721 in the ATP-binding pocket of HER3. |
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