Rineterkib

  • Chemical Properties
CAS No. 1715025-32-3 Cat. No. BCP38204
Name Rineterkib
Synonyms ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1;
Formula C26H27BrF3N5O2 M. Wt 578.4
  • Biological Activity
Description Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC (non-small celllung cancer), BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovanan cancer.
Pathways MAPK Pathway 
Targets MEK/ERK Raf 

Structure

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