Rineterkib
CAS No. | 1715025-32-3 | Cat. No. | BCP38204 |
Name | Rineterkib | ||
Synonyms | ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1; | ||
Formula | C26H27BrF3N5O2 | M. Wt | 578.4 |
Description | Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC (non-small celllung cancer), BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovanan cancer. | ||
Pathways | MAPK Pathway | ||
Targets | MEK/ERK Raf |
Structure
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