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CAS No. | 1715025-32-3 | Cat. No. | BCP38204 |
Name | Rineterkib | ||
Synonyms | ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1; | ||
SMILES | CNCC(C1=CC(=CC(=C1)Br)F)NC(=O)C2=C(C=C(C=C2)C3=NC(=CN=C3N)C4CCC(C(C4)F)O)F | ||
Chemical Name | |||
Formula | C26H27BrF3N5O2 | M. Wt | 578.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC (non-small celllung cancer), BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovanan cancer. |
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