(S)-Ceralasertib
| CAS No. | 1352226-87-9 | Cat. No. | BCP38319 |
| Name | (S)-Ceralasertib | ||
| Synonyms | (S)-AZD6738;(S)-AZD-6738;(S)-AZD 6738; | ||
| Formula | C20H24N6O2S | M. Wt | 412.51 |
| Description | (S)-Ceralasertib is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578 nM.(S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics.(S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition. | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | ATM/ATR | ||
Structure
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