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(S)-Ceralasertib New
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CAS No. | 1352226-87-9 | Cat. No. | BCP38319 |
Name | (S)-Ceralasertib | ||
Synonyms | (S)-AZD6738;(S)-AZD-6738;(S)-AZD 6738; | ||
SMILES | CC1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=N)(=O)C)C4=C5C=CNC5=NC=C4 | ||
Chemical Name | |||
Formula | C20H24N6O2S | M. Wt | 412.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (S)-Ceralasertib is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578 nM.(S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics.(S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition. |
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