Luzindole
CAS No. | 117946-91-5 | Cat. No. | BCP38322 |
Name | Luzindole | ||
Synonyms | N-0774; N0774; N 0774; N-acetyl-2-benzyltryptamine; | ||
Formula | C19H20N2O | M. Wt | 292.37 |
Description | Luzindole is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells. Luzindole inhibits the transient outward K+ current in rat cerebellar granule cells. Luzindole suppresses experimental autoimmune encephalomyelitis. | ||
Pathways | GPCR/G Protein | ||
Targets | Melatonin Receptor |
Structure
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