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CAS No. | 117946-91-5 | Cat. No. | BCP38322 |
Name | Luzindole | ||
Synonyms | N-0774; N0774; N 0774; N-acetyl-2-benzyltryptamine; | ||
SMILES | CC(=O)NCCC1=C(NC2=CC=CC=C21)CC3=CC=CC=C3 | ||
Chemical Name | |||
Formula | C19H20N2O | M. Wt | 292.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Luzindole is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells. Luzindole inhibits the transient outward K+ current in rat cerebellar granule cells. Luzindole suppresses experimental autoimmune encephalomyelitis. |
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