Trandolaprilat
| CAS No. | 87679-71-8 | Cat. No. | BCP38331 |
| Name | Trandolaprilat | ||
| Synonyms | Trandolaprilate;Trandolaprilatum; | ||
| Formula | C22H30N2O5 | M. Wt | 402.48 |
| Description | Trandolaprilat is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Trandolaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Trandolaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. | ||
| Pathways | Protease/Metabolic Enzyme Hormone Pathay | ||
| Targets | RAAS/ACE | ||
Structure
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