Trandolaprilat New
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| CAS No. | 87679-71-8 | Cat. No. | BCP38331 |
| Name | Trandolaprilat | ||
| Synonyms | Trandolaprilate;Trandolaprilatum; | ||
| SMILES | CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O | ||
| Chemical Name | |||
| Formula | C22H30N2O5 | M. Wt | 402.48 |
| Purity | 98％ | Storage | Store at 4-8°C |
| Description | Trandolaprilat is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Trandolaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Trandolaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. | ||
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