Clesacostat
| CAS No. | 1370448-25-1 | Cat. No. | BCP39030 |
| Name | Clesacostat | ||
| Synonyms | PF-05221304; PF 05221304; PF05221304; PF-5221304; PF 5221304; PF5221304; | ||
| Formula | M. Wt | ||
| Description | Clesacostat is a potent and selective ACC inhibitor (hACC1 IC50 = 13nM; hACC@ IC50 = 9 nM). PF-0522130 selectively inhibits liver DNL in animals, while demonstrating considerable safety margins against platelet reduction in a nonhuman primate model. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | ACC | ||
Structure
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