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Clesacostat Chemical Structure

Clesacostat

Data Sheet For research use only. Not for human use.
Cat. No. :BCP39030CAS No. :1370448-25-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1370448-25-1 Cat. No. BCP39030
Name Clesacostat
Synonyms PF-05221304; PF 05221304; PF05221304; PF-5221304; PF 5221304; PF5221304;
SMILES CC(C)N1C2=C(CC3(CCN(CC3)C(=O)C4=CC(=NC(=C4)OC)C5=CC=C(C=C5)C(=O)O)CC2=O)C=N1
Chemical Name
Formula M. Wt
Purity 98% Storage Store at 4-8°C
Description Clesacostat is a potent and selective ACC inhibitor (hACC1 IC50 = 13nM; hACC@ IC50 = 9 nM). PF-0522130 selectively inhibits liver DNL in animals, while demonstrating considerable safety margins against platelet reduction in a nonhuman primate model.
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