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CAS No. | 1370448-25-1 | Cat. No. | BCP39030 |
Name | Clesacostat | ||
Synonyms | PF-05221304; PF 05221304; PF05221304; PF-5221304; PF 5221304; PF5221304; | ||
SMILES | CC(C)N1C2=C(CC3(CCN(CC3)C(=O)C4=CC(=NC(=C4)OC)C5=CC=C(C=C5)C(=O)O)CC2=O)C=N1 | ||
Chemical Name | |||
Formula | M. Wt | ||
Purity | 98% | Storage | Store at 4-8°C |
Description | Clesacostat is a potent and selective ACC inhibitor (hACC1 IC50 = 13nM; hACC@ IC50 = 9 nM). PF-0522130 selectively inhibits liver DNL in animals, while demonstrating considerable safety margins against platelet reduction in a nonhuman primate model. |
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