Clesacostat New
Data Sheet
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| CAS No. | 1370448-25-1 | Cat. No. | BCP39030 |
| Name | Clesacostat | ||
| Synonyms | PF-05221304; PF 05221304; PF05221304; PF-5221304; PF 5221304; PF5221304; | ||
| SMILES | CC(C)N1C2=C(CC3(CCN(CC3)C(=O)C4=CC(=NC(=C4)OC)C5=CC=C(C=C5)C(=O)O)CC2=O)C=N1 | ||
| Chemical Name | |||
| Formula | M. Wt | ||
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Clesacostat is a potent and selective ACC inhibitor (hACC1 IC50 = 13nM; hACC@ IC50 = 9 nM). PF-0522130 selectively inhibits liver DNL in animals, while demonstrating considerable safety margins against platelet reduction in a nonhuman primate model. | ||
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