Elacestrant
| CAS号 | 722533-56-4 | 货号 | BCP39541 |
| 中文名 | Elacestrant | ||
| 英文名 | Elacestrant | ||
| 中文别名 | |||
| 英文别名 | RAD1901; RAD-1901; RAD 1901; | ||
| 分子式 | C30H38N2O2 | 分子量 | 458.63 |
| 生物活性 | Elacestrant is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). | ||
| 信号通路 | Hormone Pathay | ||
| 靶 点 | Estrogen Receptor | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！