PF429242 dihydrochloride

  • Chemical Properties
CAS No. 2248666-66-0 Cat. No. BCP39849
Name PF429242 dihydrochloride
Synonyms PF429242 dihydrochloride;PF429242 2HCl;PF 429242 2HCl;PF-429242 2HCl;
Formula C25H37Cl2N3O2 M. Wt 482.49
  • Biological Activity
Description PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice.
Related Products 947303-87-9(PF429242)
Pathways GPCR/G Protein 
Targets S1P Receptor 

Structure

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