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PF429242 dihydrochloride Chemical Structure

PF429242 dihydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP39849CAS No. :2248666-66-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2248666-66-0 Cat. No. BCP39849
Related Products 947303-87-9(PF429242)
Name PF429242 dihydrochloride
Synonyms PF429242 dihydrochloride;PF429242 2HCl;PF 429242 2HCl;PF-429242 2HCl;
SMILES CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)C3CCNC3.Cl.Cl
Chemical Name
Formula C25H37Cl2N3O2 M. Wt 482.49
Purity 98% Storage Store at 4-8°C
Description PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice.
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