IU1-47

  • Chemical Properties
CAS No. 670270-31-2 Cat. No. BCP39981
Name IU1-47
Synonyms IU1 47; IU147;
Formula C19H23ClN2O M. Wt 330.85
  • Biological Activity
Description IU1-47 is a potent and selective inhibitor of the proteasomal deubiquitinating enzyme USP14 (IC50 = 60 nM). IU1-47 has been shown to enhance protein degradation rate in cells using as a reporter the microtubule-associated protein tau.
Pathways Cell Cycle/DNA Damage 
Targets DUB 

Structure

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