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CAS No. | 670270-31-2 | Cat. No. | BCP39981 |
Name | IU1-47 | ||
Synonyms | IU1 47; IU147; | ||
SMILES | CC1=CC(=C(N1C2=CC=C(C=C2)Cl)C)C(=O)CN3CCCCC3 | ||
Chemical Name | |||
Formula | C19H23ClN2O | M. Wt | 330.85 |
Purity | 98% | Storage | Store at 4-8°C |
Description | IU1-47 is a potent and selective inhibitor of the proteasomal deubiquitinating enzyme USP14 (IC50 = 60 nM). IU1-47 has been shown to enhance protein degradation rate in cells using as a reporter the microtubule-associated protein tau. |
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