Calpain Inhibitor XII
| CAS号 | 181769-57-3 | 货号 | BCP40190 |
| 中文名 | Calpain Inhibitor XII | ||
| 英文名 | Calpain Inhibitor XII | ||
| 中文别名 | |||
| 英文别名 | (Rac)-Calpain Inhibitor XII; | ||
| 分子式 | C26H34N4O5 | 分子量 | 482.57 |
| 生物活性 | Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Proteasome | ||
结构式
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