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CAS号 | 181769-57-3 | 货号 | BCP40190 |
中文名 | Calpain Inhibitor XII | ||
英文名 | Calpain Inhibitor XII | ||
中文别名 | |||
英文别名 | (Rac)-Calpain Inhibitor XII; | ||
SMILES | CCCC(C(=O)C(=O)NCC1=CC=CC=N1)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2 | ||
化学名称 | |||
分子式 | C26H34N4O5 | 分子量 | 482.57 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. |
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