Sisunatovir HCl

CAS No.	1903763-83-6	Cat. No.	BCP40521
Name	Sisunatovir HCl
Synonyms	Sisunatovir hydrochloride;RV521 Hydrochloride;RV-521 HCl;
Formula	C23H23ClF4N4O	M. Wt	482.91

Description	Sisunatovir, also known as RV521, is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. RV521 exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Oral bioavailability in preclinical species ranged from 42 to >100% with evidence of highly efficient penetration into lung tissue. In healthy adult human volunteers experimentally infected with RSV, a potent antiviral effect was observed with a significant reduction in viral load and symptoms compared to placebo.
Related Products	1903763-82-5（Sisunatovir）
Pathways	Microbiology/Virology
Targets	RSV

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

For product details of different batches, please contact our Customer

Products are for research use only and not for human use. We do not sell to patients.