MRS 2179 tetrasodium salt
| CAS No. | 1454889-37-2 | Cat. No. | BCP40607 |
| Name | MRS 2179 tetrasodium salt | ||
| Synonyms | MRS2179 tetrasodium salt; MRS-2179 tetrasodium salt; | ||
| Formula | C11H13N5Na4O9P2 | M. Wt | 513.16 |
| Description | MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM), which is selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | P2 Receptor | ||
Structure
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