MRS 2179 tetrasodium salt New
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CAS No. | 1454889-37-2 | Cat. No. | BCP40607 |
Name | MRS 2179 tetrasodium salt | ||
Synonyms | MRS2179 tetrasodium salt; MRS-2179 tetrasodium salt; | ||
SMILES | CNC1=C2C(=NC=N1)N(C=N2)C3CC(C(O3)COP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+] | ||
Chemical Name | |||
Formula | C11H13N5Na4O9P2 | M. Wt | 513.16 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM), which is selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls. |
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