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MRS 2179 tetrasodium salt Chemical Structure

MRS 2179 tetrasodium salt

Data Sheet For research use only. Not for human use.
Cat. No. :BCP40607CAS No. :1454889-37-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1454889-37-2 Cat. No. BCP40607
Name MRS 2179 tetrasodium salt
Synonyms MRS2179 tetrasodium salt; MRS-2179 tetrasodium salt;
SMILES CNC1=C2C(=NC=N1)N(C=N2)C3CC(C(O3)COP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]
Chemical Name
Formula C11H13N5Na4O9P2 M. Wt 513.16
Purity 98% Storage Store at 4-8°C
Description MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM), which is selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro and prolongs bleeding time in rats and mice compared to controls.
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