CNX-500
| CAS No. | 1202758-21-1 | Cat. No. | BCP40963 |
| Name | CNX-500 | ||
| Synonyms | CNX500;CNX 500; | ||
| Formula | C48H68N10O9S | M. Wt | 961.18 |
| Description | CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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