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CNX-500 Chemical Structure

CNX-500

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP40963CAS No. ：1202758-21-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1202758-21-1 Cat. No. BCP40963
Name CNX-500
Synonyms CNX500;CNX 500;
SMILES CC1=CN=C(N=C1NC2=CC(=CC=C2)NC(=O)C=C)NC3=CC(=CC=C3)OCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC4C5C(CS4)NC(=O)N5
Chemical Name
Formula C48H68N10O9S M. Wt 961.18
Purity 98% Storage Store at 4-8°C
Description CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases.
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