Fasentin

  • Chemical Properties
CAS No. 392721-37-8 Cat. No. BCP41879
Name Fasentin
Synonyms N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide;
Formula C11H9ClF3NO2 M. Wt 279.64
  • Biological Activity
Description Fasentin is an inhibitor of glucose uptake, GluT1 inhibitor. Fasentin sensitizes cells to FAS-induced cell death. Fasentin selectively sensitized to death ligands, but did not decrease FLIP expression. It alters expression of genes associated with nutrient and glucose deprivation. Fasentin interacted with a unique site in the intracellular channel of the glucose transport protein GLUT1.
Pathways GPCR/G Protein 
Targets Glucose Transporter 

Structure

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