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CAS No. | 392721-37-8 | Cat. No. | BCP41879 |
Name | Fasentin | ||
Synonyms | N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide; | ||
SMILES | CC(=O)CC(=O)NC1=CC(=C(C=C1)Cl)C(F)(F)F | ||
Chemical Name | |||
Formula | C11H9ClF3NO2 | M. Wt | 279.64 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Fasentin is an inhibitor of glucose uptake, GluT1 inhibitor. Fasentin sensitizes cells to FAS-induced cell death. Fasentin selectively sensitized to death ligands, but did not decrease FLIP expression. It alters expression of genes associated with nutrient and glucose deprivation. Fasentin interacted with a unique site in the intracellular channel of the glucose transport protein GLUT1. |
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