PF07104091
| CAS号 | 2460249-19-6 | 货号 | BCP42948 |
| 中文名 | PF07104091 | ||
| 英文名 | PF07104091 | ||
| 中文别名 | |||
| 英文别名 | PF 07104091; PF07104091; PF-7104091; PF 7104091; PF7104091; | ||
| 分子式 | C19H28N6O4 | 分子量 | 404.46 |
| 生物活性 | PF-07104091 is an orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity. Upon administration, CDK2 inhibitor PF-07104091 selectively targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation and are frequently overexpressed in tumor cells. CDK2/cyclin E complex plays an important role in retinoblastoma (Rb) protein phosphorylation and the G1-S phase cell cycle transition. CDK2/cyclin A complex plays an important role in DNA synthesis in S phase and the activation of CDK1/cyclin B for the G2-M phase cell cycle transition. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | CDK | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！