PF07104091 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP42948CAS号：2460249-19-6纯度：98%

规格	价格(CNY)	是否现货	购买咨询
5.00 mg	￥2000.00	In-stock	购买咨询
10.00 mg	￥3300.00	In-stock	购买咨询
50.00 mg	￥4500.00	In-stock	购买咨询

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CAS号	2460249-19-6	货号	BCP42948
中文名	PF07104091
英文名	PF07104091
中文别名
英文别名	PF 07104091; PF07104091; PF-7104091; PF 7104091; PF7104091;
SMILES	O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2
化学名称
分子式	C19H28N6O4	分子量	404.46
纯度	98%	配送	惯例下常温包邮
产品描述	PF-07104091 is an orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity. Upon administration, CDK2 inhibitor PF-07104091 selectively targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation and are frequently overexpressed in tumor cells. CDK2/cyclin E complex plays an important role in retinoblastoma (Rb) protein phosphorylation and the G1-S phase cell cycle transition. CDK2/cyclin A complex plays an important role in DNA synthesis in S phase and the activation of CDK1/cyclin B for the G2-M phase cell cycle transition.