CC-90010
| CAS号 | 1706738-98-8 | 货号 | BCP43205 |
| 中文名 | CC-90010 | ||
| 英文名 | CC-90010 | ||
| 中文别名 | |||
| 英文别名 | Trotabresib; CC 90010; CC90010; | ||
| 分子式 | C21H21NO4S | 分子量 | 383.46 |
| 生物活性 | CC-90010 is a potent and orally active BET inhibitor. CC-90010 preferentially binds to the second bromodomain (BD2) of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histones. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of proliferation in BET-overexpressing tumor cells. | ||
| 信号通路 | Epigenetics | ||
| 靶 点 | Epigenetic Reader Domain | ||
结构式
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