IT-603
| CAS No. | 292168-90-2 | Cat. No. | BCP43206 |
| Name | IT-603 | ||
| Synonyms | (E/Z)-IT-603;IT603;IT 603; | ||
| Formula | C11H9BrN2O3S | M. Wt | 329.17 |
| Description | (E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases. | ||
| Pathways | NFκB | ||
| Targets | NF κB | ||
Structure
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