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IT-603 Chemical Structure

IT-603

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43206CAS No. :292168-90-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 292168-90-2 Cat. No. BCP43206
Name IT-603
Synonyms (E/Z)-IT-603;IT603;IT 603;
SMILES COC1=CC(=CC(=C1O)C=C2C(=O)NC(=S)N2)Br
Chemical Name
Formula C11H9BrN2O3S M. Wt 329.17
Purity 98% Storage Store at 4-8°C
Description (E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases.
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