OT-82
CAS No. | 1800487-55-1 | Cat. No. | BCP43333 |
Name | OT-82 | ||
Synonyms | OT82;OT 82; | ||
Formula | C26H21FN4O | M. Wt | 424.47 |
Description | OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models. | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | Nampt |
Structure
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