OT-82

  • Chemical Properties
CAS No. 1800487-55-1 Cat. No. BCP43333
Name OT-82
Synonyms OT82;OT 82;
Formula C26H21FN4O M. Wt 424.47
  • Biological Activity
Description OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.
Pathways Protease/Metabolic Enzyme 
Targets Nampt 

Structure

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