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OT-82 Chemical Structure

OT-82

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43333CAS No. :1800487-55-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1800487-55-1 Cat. No. BCP43333
Name OT-82
Synonyms OT82;OT 82;
SMILES C1=CC(=CC=C1C#CC2=C(C=CC(=C2)C(=O)NCCCC3=CNN=C3)C4=CC=NC=C4)F
Chemical Name
Formula C26H21FN4O M. Wt 424.47
Purity 98% Storage Store at 4-8°C
Description OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.
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