Pracinostat Dihydrochloride
| CAS号 | 929016-98-8 | 货号 | BCP43352 |
| 中文名 | Pracinostat Dihydrochloride | ||
| 英文名 | Pracinostat Dihydrochloride | ||
| 中文别名 | |||
| 英文别名 | Pracinostat 2HCl; Fezolinetant; ESN-364; ESN 364; ESN364; | ||
| 分子式 | C20H32Cl2N4O2 | 分子量 | 431.4 |
| 生物活性 | Pracinostat, also known as SB939, is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. | ||
| 信号通路 | Cell Cycle/DNA Damage Epigenetics | ||
| 靶 点 | HDAC | ||
结构式
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