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| CAS号 | 929016-98-8 | 货号 | BCP43352 |
| 中文名 | Pracinostat Dihydrochloride | ||
| 英文名 | Pracinostat Dihydrochloride | ||
| 中文别名 | |||
| 英文别名 | Pracinostat 2HCl; Fezolinetant; ESN-364; ESN 364; ESN364; | ||
| SMILES | CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO.Cl.Cl | ||
| 化学名称 | |||
| 分子式 | C20H32Cl2N4O2 | 分子量 | 431.4 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Pracinostat, also known as SB939, is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. | ||
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