ARP100
| CAS No. | 704888-90-4 | Cat. No. | BCP43419 |
| Name | ARP100 | ||
| Synonyms | ARP-100; ARP 100; | ||
| Formula | C17H20N2O5S | M. Wt | 364.42 |
| Description | ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM). | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | MMP | ||
Structure
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